A 10-year-old presents with a single painful ulcer on the inner cheek mucosa; most likely diagnosis and treatment?

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Multiple Choice

A 10-year-old presents with a single painful ulcer on the inner cheek mucosa; most likely diagnosis and treatment?

Explanation:
A single painful ulcer on the inner cheek in a child is most consistent with a minor aphthous ulcer. These “canker sores” are typically small, shallow, round to oval ulcers with a yellow-gray base and a red halo, and they occur on nonkeratinized movable mucosa such as the buccal or labial mucosa. They are painful but heal spontaneously within about 1–2 weeks, and recurrence is common. The best treatment is a topical corticosteroid to reduce the local inflammatory response and speed healing. Triamcinolone in an adhesive base (Orabase) is commonly used; apply a small amount directly to the ulcer a few times daily, avoiding eating for about 15 minutes after application. Good supportive care includes maintaining oral hygiene, avoiding irritants (spicy or acidic foods), and using gentle rinses or topical anesthetics if needed for pain. Why the other options fit less well: herpes simplex stomatitis usually presents with multiple vesicular/ulcerative lesions and often involves gingiva, with fever and systemic symptoms; antiviral therapy like acyclovir is considered for HSV infections but the presentation here is a solitary ulcer on buccal mucosa, not typical HSV stomatitis. Herpangina causes small ulcers on the posterior oral cavity (soft palate and tonsillar areas) and is often accompanied by fever and malaise, not a single buccal ulcer. Hand, foot, and mouth disease features multiple oral ulcers plus characteristic hand/foot involvement and is viral in origin; antibiotic mouthwash would not be appropriate.

A single painful ulcer on the inner cheek in a child is most consistent with a minor aphthous ulcer. These “canker sores” are typically small, shallow, round to oval ulcers with a yellow-gray base and a red halo, and they occur on nonkeratinized movable mucosa such as the buccal or labial mucosa. They are painful but heal spontaneously within about 1–2 weeks, and recurrence is common.

The best treatment is a topical corticosteroid to reduce the local inflammatory response and speed healing. Triamcinolone in an adhesive base (Orabase) is commonly used; apply a small amount directly to the ulcer a few times daily, avoiding eating for about 15 minutes after application. Good supportive care includes maintaining oral hygiene, avoiding irritants (spicy or acidic foods), and using gentle rinses or topical anesthetics if needed for pain.

Why the other options fit less well: herpes simplex stomatitis usually presents with multiple vesicular/ulcerative lesions and often involves gingiva, with fever and systemic symptoms; antiviral therapy like acyclovir is considered for HSV infections but the presentation here is a solitary ulcer on buccal mucosa, not typical HSV stomatitis. Herpangina causes small ulcers on the posterior oral cavity (soft palate and tonsillar areas) and is often accompanied by fever and malaise, not a single buccal ulcer. Hand, foot, and mouth disease features multiple oral ulcers plus characteristic hand/foot involvement and is viral in origin; antibiotic mouthwash would not be appropriate.

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