Which antibiotic is the primary treatment for gonorrhea in the provided material?

Which antibiotic is the primary treatment for gonorrhea in the provided material?

• A. Amoxicillin
• B. Ceftriaxone
• C. Ofloxacin
• D. Penicillin

Answer: (B)

Gonorrhea is best treated with an antibiotic that remains reliably effective against Neisseria gonorrhoeae despite rising resistance. Ceftriaxone, a third‑generation cephalosporin given by intramuscular injection, provides strong bactericidal activity by inhibiting cell wall synthesis and achieves high levels in serum and genital tissues. It remains the first-line choice because older options like penicillin and amoxicillin are no longer effective due to widespread beta-lactamase production and resistance, and fluoroquinolones such as ofloxacin have lost their effectiveness because of resistance. In practice, ceftriaxone is used as the primary treatment, often with additional therapy if a chlamydial coinfection is suspected.

Gonorrhea is best treated with an antibiotic that remains reliably effective against Neisseria gonorrhoeae despite rising resistance. Ceftriaxone, a third‑generation cephalosporin given by intramuscular injection, provides strong bactericidal activity by inhibiting cell wall synthesis and achieves high levels in serum and genital tissues. It remains the first-line choice because older options like penicillin and amoxicillin are no longer effective due to widespread beta-lactamase production and resistance, and fluoroquinolones such as ofloxacin have lost their effectiveness because of resistance. In practice, ceftriaxone is used as the primary treatment, often with additional therapy if a chlamydial coinfection is suspected.