Which finding is commonly associated with pediatric Cushing syndrome?

Which finding is commonly associated with pediatric Cushing syndrome?

• A. Turner’s syndrome
• B. Beckwith-Wiedemann syndrome
• C. Marfan syndrome
• D. Moon facies

Answer: (D)

Cushing syndrome in children causes fat redistribution that gives a round, full face. This facial fullness, or moon facies, is a classic sign from cortisol excess, often accompanied by truncal obesity and other features like a dorsocervical fat pad. The other conditions listed are not typical manifestations of Cushing and have distinct syndromic features (Turner with short stature and neck webbing; Beckwith-Wiedemann with macrosomia and organomegaly; Marfan with tall stature and arachnodactyly). Thus, moon facies best fits pediatric Cushing syndrome.

Cushing syndrome in children causes fat redistribution that gives a round, full face. This facial fullness, or moon facies, is a classic sign from cortisol excess, often accompanied by truncal obesity and other features like a dorsocervical fat pad. The other conditions listed are not typical manifestations of Cushing and have distinct syndromic features (Turner with short stature and neck webbing; Beckwith-Wiedemann with macrosomia and organomegaly; Marfan with tall stature and arachnodactyly). Thus, moon facies best fits pediatric Cushing syndrome.